Could an ancient signaling pathway hold the key to tooth formation?
Researchers at the University of Zurich Center for Dental Medicine recently studied the Notch pathway’s role in the evolution of tooth morphology, with their results being published in Cellular and Molecular Life Sciences. The team, led by Thimios Mitsiadis, PhD, suggested that mutations in this ancient signaling pathway can lead to defective structures in tooth enamel. Tooth analysis is often performed to study mammalian evolution and the adaptations that occur

