Mannitol makes dental anesthesia more effective
Combining mannitol with lidocaine significantly increases the effectiveness of an inferior alveolar nerve block, according to a new study in Anesthesia Progress (Spring 2013, Vol. 60:1, pp. 3-10). A team of researchers from Ohio State University tested the efficacy of lidocaine with epinephrine compared with equal amounts of lidocaine with epinephrine plus mannitol. After injecting the anesthetic, the subjects’ teeth were electric pulp-tested for sensation. The researchers also measured pain

