Pearl announced that it has raised US$58m in Series B funding, in what is said to be the largest investment ever in dental artificial intelligence, to accelerate its mission to elevate patient care in dentistry. The round for Pearl AI was led by Left Lane Capital led with participation from Smash Capital, Alpha Partners, and existing investors, Craft Ventures and Neotribe Ventures.
With this investment, Pearl will continue to advance innovation in technologies that enhance the health of dental patients around the world by expanding its line of dental AI products, broadening its regulatory and patent portfolio, and increasing global access to the benefits of AI in dentistry.

According to Pearl, its machine learning and computer vision tools currently solve a the challenge of inconsistency in diagnostic accuracy in dentistry, which directly impacts the quality of patient care. The company’s AI serves as a real-time aid to help dentists read patient x-rays, deliver consistent, objective, and accurate diagnoses, and clearly communicate findings to patients with precision, clarity, and confidence.
Since receiving the first-ever FDA clearance for AI software to help dental professionals detect multiple different pathologies and other conditions in x-rays, Pearl’s clinical AI has gained regulatory authorisations for chairside use in over 120 countries and recognition among TIME’s Best Inventions.
The company plans to use the funding both to accelerate ongoing development of computer vision capabilities — including detection and tracking of disease in 3D and other imaging modalities — and introduce new AI tools to improve patient treatment planning, insurance claim approvals and dental education.
“In the field of healthcare, dentistry has become an AI standard-bearer, demonstrating the technology’s enormous utility and benefit in day-to-day patient care — and Pearl has led the AI charge in dentistry,” said Ophir Tanz, founder and CEO of Pearl. “This historic funding round underscores the impact of Pearl’s capabilities and supports our belief that high-quality, AI-powered dental care should be accessible to everyone. With this investment, Pearl will continue to push the envelope, providing pioneering machine learning to improve oral health outcomes and strengthen trust between the patient and dental professionals.”
According to Pearl, this investment follows a period of significant growth. The company reportedly grew its revenue by 458% in 2023. Pearl’s technology is used in dental practices across six continents and is commercially available to over 500,000 dental practices and millions of dental professionals worldwide. The company has also integrated its AI into dozens of popular imaging and practice management systems and is the preferred radiologic AI provider for leading dental technology distributors. “We have spent the past year evaluating this market and it is clear that Pearl stands above peers at the forefront of dental innovation,” said Vinny Pujji, managing partner at Left Lane Capital. “Pearl’s pioneering dental Al improves diagnostic accuracy and efficiency while transforming the provider-patient relationship. We are confident in Pearl’s ability to continue setting new standards of care and are thrilled to support their next phase of growth.”
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