Smartee Denti-Technology today released its 2025 annual review, detailing a pivotal year characterized by the worldwide clinical application of its proprietary mandibular repositioning technology, the inauguration of new European infrastructure, and a strategic partnership with the Straumann Group.
The 2025 review highlights Smartee’s transition from rapid growth to sustained maturity, underscored by advancements in three key pillars: clinical efficacy, global supply chain capability, and professional education.
Clinical Milestone: Applying Mandibular Repositioning at Scale
A central achievement of 2025 was crossing the 100,000-case threshold for Smartee GS Mandibular Repositioning technology. This volume represents significant real-world evidence supporting the efficacy of using clear aligners to treat severe jaw discrepancies, specifically Class II and Class III malocclusions, through mandibular repositioning rather than traditional extraction or surgical mechanics.
Academic recognition of this approach accelerated throughout the year. The Journal of Aligner Orthodontics (JAO) published two separate papers on Smartee’s protocols. Issue 2, 2025 featured a report by Dr. Xingxing Wang, Smartee Medical Director, on the treatment of Class II malocclusion with sagittal-guidance twin block clear aligners (S8-SGTB). Issue 4, 2025 included a research paper titled “Working Mechanism and Clinical Management of Mandibular Advancement Repositioning Technology in Treating Three-Depth Malocclusion in Adult Patients” by Prof. Gang Shen, Smartee GS Chief Scientist, and his orthodontic team, further documenting clinical outcomes.
In 2025, Smartee expanded its production capacity to meet growing international demand by launching a new 100,000-square-meter intelligent manufacturing campus. The facility features fully automated production lines with modular scalability and supports both internal product lines and external partners.
This capability was validated in October through a strategic partnership with the Straumann Group. Under the agreement, Smartee will provide manufacturing support for Straumann’s clear aligner brand, ClearCorrect, in selected EMEA and APAC markets, leveraging its advanced infrastructure to ensure customized production and product consistency.
In the fourth quarter of 2025, Smartee diversified its clinical portfolio with two major technological launches. Smartee Sleep Aligners, introduced on October 1, marked the company’s entry into the sleep apnea device market, targeting mild-to-moderate Obstructive Sleep Apnea-Hypopnea Syndrome. The system features a patented digital twin-splint locking mechanism for mandibular advancement and an ultra-thin 1 mm profile designed for improved comfort. The device is engineered to expand the oropharyngeal airway by up to 23% and is available in two versions: SA for standalone sleep therapy and SA Plus, which combines airway management with simultaneous orthodontic tooth movement.
On October 30, Smartee launched Live 3D, an AI-driven treatment planning tool designed to improve digital workflow efficiency. Using deep learning algorithms, Live 3D generates initial 3D treatment designs within 30 minutes. When paired with Smartee LiveUpdate, clinicians can progress from case upload to final approval in under one hour, significantly reducing production turnaround time.
To support its expanding European footprint, Smartee established a UK subsidiary and opened the European Orthodontic Clinical Support Center in Stoke-on-Trent. The center provides localized treatment planning and clinical support aligned with regional medical standards and biomechanical preferences.
Smartee’s commitment to professional education remained strong in 2025, with participation in 27 major international congresses and extensive proprietary training programs. The Smartee GS lecture series reached 17 cities worldwide, training more than 11,000 professionals. In China, domestic programs engaged 14,330 participants, extending advanced orthodontic education into emerging regional markets. Smartee also hosted pediatric early orthodontics and orofacial myofunctional therapy summits across Asia-Pacific and Europe.
Alongside these initiatives, Smartee advanced its ESG commitments, implementing solar energy projects projected to reduce annual CO₂ emissions by 209 tons and deploying digital governance systems to support employee wellness.
About Smartee Denti-Technology
Founded in 2004, Smartee is a global leader in digital orthodontics and clear aligner manufacturing. With four R&D centers and four manufacturing bases across China and Spain, Smartee serves more than 99,000 partner doctors in 57 countries, offering a portfolio that includes the Smartee GS, Smartee GE, and Smartee Kinder/Teen series.
