Clinical portfolio for the brand shows TheraBreath™ Healthy Gums Toothpaste significantly outperforms Crest Regular across gingival inflammation, plaque prevention, bleeding reduction, and malodor control.

TheraBreath™, the #1 alcohol-free mouthrinse brand and a Church & Dwight oral care brand, unveiled the results of eight clinical research studies through poster presentations supporting its new TheraBreath™ Toothpaste line at the International Association for Dental, Oral, and Craniofacial Research (IADR) 104th General Session, held March 25–28, 2026, in San Diego, California. The studies represent the brand’s first comprehensive, science-based clinical portfolio for toothpaste, delivering independently conducted clinical evidence across its new flagship products.
The research spans gum health, plaque prevention, malodor reduction, whitening, and enamel protection—marking a significant expansion for a brand long trusted by dental professionals for its popular alcohol-free mouthrinse line, now bringing that same science-backed standard to toothpaste. Highlights include:
- Gum Health and Bleeding Reduction: TheraBreath Healthy Gums Toothpaste (SnF₂) reduced gum bleeding by 70% vs. baseline after 12 weeks and outperformed Crest Regular Toothpaste at every time point (p<0.0001). After eight weeks, 100% of participants showed at least a 50% improvement in bleeding from baseline.
- Plaque Prevention: TheraBreath Healthy Gums Toothpaste prevented 65% more plaque buildup than Crest Regular at Day 1 and was 139% more effective at the gumline by Day 14, with consistent results even in hard-to-reach areas.
- Malodor Reduction: TheraBreath Healthy Gums Toothpaste virtually eliminated bad breath in 93–95% of users at peak time points vs. just 4–6% for Crest Regular, reducing oral malodor by a minimum of 70% from baseline across all measured time points over seven days.
- Whitening: TheraBreath Whitening Toothpaste (NaF formula) reduced surface stains 50% better than Crest Regular Toothpaste after two weeks and 65% better after six weeks—without peroxide.
“IADR is where the dental research community sets the standard for evidence-based care, and we’re proud to contribute to that conversation. These eight studies mark a turning point for TheraBreath™, establishing a clinical foundation for our new toothpaste line that validates what patients have experienced for decades with our rinses, and gives clinicians the data to match,” stated Annahita Ghassemi, Sr. Director of Global Product Safety and Clinical Research, Church & Dwight Co., Inc.
All eight posters—covering the full range of clinical studies presented at IADR—are available for download at hygienesquad.com/therabreath/resources-education/#research.
TheraBreath™ Clinical Posters Presented at IADR 2026:
- Healthy Gums SnF₂ — 3-Month Plaque & Gingivitis Study (vs. Crest Regular NaF)
- Healthy Gums SnF₂ — Malodor Reduction Study (vs. Crest Regular NaF)
- Healthy Gums SnF₂ — Plaque Prevention Study (vs. Crest Regular NaF)
- Healthy Gums SnF₂ — Modified PGRM Study
- Healthy Gums SnF₂ — Intra-Oral Appliance (IOA) Study
- TheraBreath Whitening — Extrinsic Stain Removal Study
- TheraBreath Whitening — Intra-Oral Appliance (IOA) Study
- TheraBreath Sensitive — Intra-Oral Appliance (IOA) Study
About TheraBreath
In 2021, the TheraBreath brand was acquired by Church & Dwight Co., Inc., becoming the latest addition to its family of oral care products that include Waterpik™ water flossers, ARM & HAMMER™ toothpaste, and Spinbrush™ toothbrushes. Founded by Dr. Harold Katz at the California Breath Clinics over 30 years ago, TheraBreath grew into the #1 alcohol-free mouthrinse brand by targeting the germs that cause bad breath. Today, TheraBreath has expanded its science-backed approach across an extensive line of oral care products that include toothpastes addressing gum health, teeth whitening, cavity prevention, sensitivity relief, and dry mouth symptoms. Learn more at www.therabreath.com.
About IADR/AADOCR
The International Association for Dental, Oral, and Craniofacial Research (IADR) is a nonprofit organization with a mission to drive dental, oral, and craniofacial research for health and well-being worldwide. IADR represents individual scientists, clinician-scientists, dental professionals, and students based in academic, government, nonprofit, and private-sector institutions who share this mission. The American Association for Dental, Oral, and Craniofacial Research (AADOCR) is the largest division of IADR. Learn more at www.iadr.org.

