In addition to experiencing rapid weight loss and a significant loss of appetite, people who use GLP-1 diet pills such as Ozempic and Mounjaro may also experience strong side effects such as nausea, vomiting or diarrhea.
But there is a potential problem that is less taken seriously and is attracting the attention of dental experts: these drugs may have a serious impact on oral health.
This phenomenon is called “Oldsmobile mouth” or “Oldsmobile teeth.” Dr. Elizabeth Walton, co-founder and clinical director of Risas Kids Dental in Phoenix, pointed out in an interview with The Washington Post that the main problem comes from the increase in dry mouth symptoms.
“GLP-1 drugs significantly reduce saliva secretion,” Walton explained. “Saliva is essential for protecting the oral environment. It can neutralize oral acidity, clean food debris and help remineralize tooth enamel.” But these drugs inhibit salivary gland function and reduce thirst, further weakening saliva secretion.
The result of dry mouth is increased bacterial growth, which in turn increases the risk of tooth decay and gum diseases such as gingivitis and periodontitis. Gingivitis is an inflammation of the surface of the gums. If left untreated, it may develop into a more serious periodontitis, which can damage the supporting tissues of the teeth.
To prevent these oral problems, Walton recommends that GLP-1 drug users pay special attention to hydration. She recommends drinking 2 to 3 liters of water (about 64 to 100 ounces) a day and using sugar-free gum to promote saliva secretion.
Oral sprays, moisturizing gels and mouthwashes such as Biotène on the market can also relieve dry mouth. Among them, Biotène gel is praised by Walton as the most effective, but it needs to be reapplied frequently.
In addition, patients should try to avoid foods and drinks that are easy to cause dry mouth, including alcohol, caffeinated drinks, sports drinks, salty foods, pickled meats, asparagus, and sugary juices. Spicy foods should also be consumed with caution to prevent irritation of the mouth and aggravation of dryness symptoms.
GLP-1 drugs also often cause nausea and vomiting, which can also cause damage to the mouth. After vomiting, the pH value in the mouth drops sharply, exposing the teeth to an acidic environment, increasing the risk of enamel corrosion and tooth decay. Walton reminds that you should not brush your teeth immediately after vomiting to avoid damaging the natural protective film on the surface of your teeth.
“It is recommended to rinse your mouth with clean water and wait one to two hours before brushing your teeth,” she said. “This helps the pH of the mouth to recover naturally and protects the teeth from further damage.”
Another side effect that cannot be ignored is a change in taste. Some patients may experience a bitter or metallic taste in their mouths, a phenomenon known as “Ozemike tongue.”
The cause may be related to reduced saliva secretion, mild ketosis, or bile reflux. In this regard, Walton recommends using sugar-free chewing gum to stimulate saliva production and relieve odor.
She emphasized that any abnormal oral symptoms that occur during medication should be communicated with dentists and doctors in a timely manner. “In the pursuit of healthy weight loss, dentists are your indispensable support. We can help you complete this journey more safely and comfortably.”